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[Chemical Constituents of Datura Stramonium Seeds]

[Chemical Constituents of Datura Stramonium Seeds]

Jianwen Li, Binbin Lin, Guokai Wang, Hongjie Gao, Minjian Qin

Zhongguo Zhong Yao Za Zhi. 2012 Feb;37(3):319-22.

PMID: 22568232

Abstract:

Objective:
To study chemical constituents in the seeds of Datura Stramonium (Solanaceae family).
Method:
Compounds were isolated and purified by silica gel, MCI and Sephadex LH-20 column chromatography, and their structures were determined based on physicochemical constants and spectroscopic analysis including NMR and MS.
Result:
Twelve compounds were isolated and identified from Datura stramonium, they were N-trans-feruloyl tryptamine (1), hyoscyamilactol (2), scopoletin (3), umckalin (4), daturaolone (5), daturadiol (6), N-trans-ferulicacyl- tyramine (7), cleomiscosin A (8), fraxetin (9), scopolamine (10), 1-Acetyl-7-hydrox-beta-carbol-ine (11), 7-hydroxy-beta-carbolinel-propionic acid (12).
Conclusion:
Compound 2, 7, 9 and 12 were obtained from Datura genus for the first time, whereas compound 1, 4, 8 and 11 were obtained from the Solanaceae family for the first time.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP43053629	Umckalin		43053-62-9	Price

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