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Chemicals, Nutrition, and Autism Spectrum Disorder: A Mini-Review

Takeo Fujiwara, Naho Morisaki, Yukiko Honda, Makiko Sampei, Yukako Tani

Front Neurosci. 2016 Apr 20;10:174.

PMID: 27147957

Abstract:

The rapid increase of the prevalence of autism spectrum disorder (ASD) suggests that exposure to chemicals may impact the development of ASD. Therefore, we reviewed literature on the following chemicals, nutrient to investigate their association with ASD: (1) smoke/tobacco, (2) alcohol, (3) air pollution, (4) pesticides, (5) endocrine-disrupting chemicals, (6) heavy metals, (7) micronutrients, (8) fatty acid, and (9) parental obesity as a proxy of accumulation of specific chemicals or nutritional status. Several chemical exposures such as air pollution (e.g., particular matter 2.5), pesticides, bisphenol A, phthalates, mercury, and nutrition deficiency such as folic acid, vitamin D, or fatty acid may possibly be associated with an increased risk of ASD, whereas other traditional risk factors such as smoking/tobacco, alcohol, or polychlorinated biphenyls are less likely to be associated with ASD. Further research is needed to accumulate evidence on the association between chemical exposure and nutrient deficiencies and ASD in various doses and populations.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
IAR42410583 Vitamin K1-4a,5,6,7,8,8a-13C6 Vitamin K1-4a,5,6,7,8,8a-13C6 Price
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