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Clinical Efficacy Evaluation of a Novel Barrier Protection Cream

Clinical Efficacy Evaluation of a Novel Barrier Protection Cream

Herbert B Slade, Joseph Fowler, Zoe Diana Draelos, Barry T Reece, D Innes Cargill

Cutis. 2008 Oct;82(4 Suppl):21-8.

PMID: 19202673

Abstract:

COR806.805 (Tetrix Cream) is a new barrier cream formulated using a unique patented technology. As a water-in-oil emulsion, COR806.805 has a water-resistant outer surface and water-soluble inner surface. Clinical studies have demonstrated the safety of COR806.805 in healthy adults with respect to sensitization, irritation, and effect on the healing of existing skin lesions. We report the results of trials undertaken to explore the substantivity and barrier protection properties of this new product when applied to clinically normal skin, as well as the beneficial effects when applied to inflamed skin, including skin affected by eczema. The results indicate that the cream establishes a barrier against common irritants, with persistence over 6 hours. The product appears effective and well-tolerated as a barrier and also may provide benefit in managing the itching and burning associated with contact dermatitis.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP540976-A	Cyclomethicone 6		540-97-6	Price

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