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Clobetasone Butyrate and Hydrocortisone Butyrate in the Treatment of Eczema: A Double-Blind Comparison

A Lassus

Curr Med Res Opin. 1979;6(3):165-7.

PMID: 391489

Abstract:

Forty patients with symmetrical eczematous lesions on their extremities were treated in a double-blind fashion with 0.05% clobetasone butyrate and 0.1% hydrocortisone butyrate in cream bases. After 2 weeks of treatment, a preference for clobetasone butyrate was observed in 7 cases, for hydrocortisone butyrate in 9 cases and in 24 cases both sides responded equally. The lesions on both sides improved steadily throughout the study in all cases. When completing the trial after 2-weeks' treatment, the clobetasone butyrate-treated lesions had healed in 8 cases and the hydrocortisone butyrate-treated lesions in 10 cases. No local side-effects were observed.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP13609671 Hydrocortisone butyrate Hydrocortisone butyrate 13609-67-1 Price
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