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Clofazimine. A New Agent for the Treatment of Pyoderma Gangrenosum

G Michaëlsson, L Molin, S Ohmann, L Gip, B Lindström, M Skogh, I Trolin

Arch Dermatol. 1976 Mar;112(3):344-9.

PMID: 1259447

Abstract:

Eight patients had pyoderma gangrenosum. They were given a phendimetrazine tartrate derivative, clofazimine (Lamprene [Britain]), which is a chemotherapeutic agent used mainly in certain mycobacterial infections and which also has phagocytosis-enhancing properties. The effect of this drug was remarkably good, with rapid healing of the lesions commencing 3 to 14 days after treatment was started. The mechanism for the effect of clofazimine in pyoderma gangrenosum is not known.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP50588-B Phendimetrazine tartrate Phendimetrazine tartrate 50-58-8 Price
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