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Closure of the Cavity in Permethylated Cyclodextrins Through Glucose Inversion, Flipping, and Kinking

Thomas Steiner, Wolfram Saenger

Angew Chem Int Ed Engl. 1998 Dec 31;37(24):3404-3407.

PMID: 29711281

Abstract:

Glucose-flips in a small cycloamylose: the molecular structure of permethylated γ-cyclodextrin, which crystallizes as the dihydrate, is characterized by 180° flips of two diametrically opposed glucose residues. This leads to an elliptical distortion of the molecule and closure of the molecular cavity on one side so that it is no longer doughnut-shaped but is bowl-shaped. The hydrate water molecules are not located in the cavities!

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP91464903 γ-Cyclodextrin hydrate γ-Cyclodextrin hydrate 91464-90-3 Price
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