Home
Resources
Publications
Comparative Evaluation of Skin Moisture After Topical Application of 10% and 30% Lactobionic Acid

Comparative Evaluation of Skin Moisture After Topical Application of 10% and 30% Lactobionic Acid

Barbara Algiert-Zielińska, Paulina Mucha, Helena Rotsztejn

J Cosmet Dermatol. 2018 Dec;17(6):1096-1100.

PMID: 29318715

Abstract:

Background:
Dry skin is characterized by symptoms such as itching, redness, excessive exfoliation. These symptoms cause discomfort and contribute to secondary bacterial infections. Dry skin treatments are based on topical applications of various formulations. Among many of them are polyhydroxy acids, which recently gained more attention.
Aims:
The aim of this study was a comparative assessment of hydration level (corneometric) after application of lactobionic acid (LA) in the form of peel at concentrations of 10% and 30%.
Material and methods:
The study involved 10 Caucasian individuals aged 26-73 years. Eight treatments were performed at weekly intervals. The peels were applied using the "Split face" method-on the left side of the face 10% LA, and the right side 30% LA which consisted of specified concentration of LA, deionized water, xanthan gum, ethoxydiglycol. The test subjects received a 5% LA cream for overnight use. The cream consisted of deionized water, LA, isopropyl palmitate, ascorbyl palmitate, methylparaben. The products for this study were provided by Grehen Ltd. Celestynów, Poland. Prior to each procedure, the skin hydration level was measured using Corneometer CM 825 from Courage + Khazaka electronic GmbH.
Results:
There was a statistically significant improvement in hydration level after 8 treatments for all measuring points and both concentrations. The difference of the skin hydration level between 10% LA and 30% LA could not be determined.
Conclusions:
Lactobionic acid is a highly moisturizing agent. There was no significant difference in moisturizing effect between 10% LA concentration and 30% LA concentration.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP142916-1-A	Isopropyl palmitate		142-91-6	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: