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Comparative Investigation of Umbellularia Californica and Laurus Nobilis Leaf Essential Oils and Identification of Constituents Active Against Aedes Aegypti

Comparative Investigation of Umbellularia Californica and Laurus Nobilis Leaf Essential Oils and Identification of Constituents Active Against Aedes Aegypti

Nurhayat Tabanca, Cristina Avonto, Mei Wang, Jon F Parcher, Abbas Ali, Betul Demirci, Vijayasankar Raman, Ikhlas A Khan

J Agric Food Chem. 2013 Dec 18;61(50):12283-91.

PMID: 24266426

Abstract:

Umbellularia californica (California bay laurel) and Laurus nobilis (Mediterranean bay laurel) leaves may be mistaken or used as a substitute on the market due to their morphological similarity. In this study, a comparison of anatomical and chemical features and biological activity of both plants is presented. L. nobilis essential oil biting deterrent and larvicidal activity were negligible. On the other hand, U. californica leaf oil showed biting deterrent activity against Aedes aegypti . The identified active repellents was thymol, along with (-)-umbellulone, 1,8-cineole, and (-)-α-terpineol. U. californica essential oil also demonstrated good larvicidal activity against 1-day-old Ae. aegypti larvae with a LD50 value of 52.6 ppm. Thymol (LD50 = 17.6 ppm), p-cymene, (-)-umbellulone, and methyleugenol were the primary larvicidal in this oil. Umbellulone was found as the principal compound (37%) of U. californica essential oil, but was not present in L. nobilis essential oil. Umbellulone mosquito activity is here reported for the first time.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP546781	(-)-Umbellulone		546-78-1	Price

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