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Comparative Studies on the Implantation of Nano Platinum Black and Pure Platinum Electrodes in the Rabbit Orbicularis Oculi Muscle

Y Zhang, K Y Li, C Jin, Y T Wang, L Geng, Y J Sun, H C Tian, J Q Liu, X J Jin

J Laryngol Otol. 2014 Aug;128(8):679-89.

PMID: 25084097

Abstract:

Objective:
To study the interactive influence of implanted nano platinum black electrodes (as compared with pure platinum electrodes) on rabbit orbicularis oculi muscle morphology and function.
Methods:
The influence of the two types of electrode on the orbicularis oculi muscle was monitored in a rabbit model of facial paralysis. Biological electric current and exciting current were administered to biological tissue, and morphological and functional changes were identified. Changes in orbicularis oculi muscle contraction, electrode configuration and performance associated with long-term electrical stimulation were observed over 28 days of implantation.
Results:
The nano platinum black electrode was superior to the pure platinum electrode in the following aspects: morphology and functionality, electrical excitation function of the orbicularis oculi muscle (as assessed by electromyography), muscle contraction function and biological tissue changes. Furthermore, the nano platinum black electrode features had good stability.
Conclusion:
Microelectrode surface modification with nano platinum black can effectively increase the microelectrode surface area and improve electrode performance, and is associated with good tissue compatibility.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP7440064-A Platinum black Platinum black 7440-06-4 Price
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