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[Comparison of the Effects Between Maize Germ Oil and Lard Oil Loading on Blood Lipids and Fatty Acid Profile of Mice]

[Comparison of the Effects Between Maize Germ Oil and Lard Oil Loading on Blood Lipids and Fatty Acid Profile of Mice]

Lixin Na, Yuqiu Zhang, Li Li, Boxue Wu, Yucun Niu, Rennan Feng

Wei Sheng Yan Jiu. 2013 Sep;42(5):809-13.

PMID: 24218890

Abstract:

Objective:
To investigate the changes in blood lipids and fatty acids profile of mice after different oil loading, and explore the effects of different dietary fatty acids on postprandial blood lipids and fatty acid profile.
Methods:
Ninety-six C57BL/6 mice were randomly divided into 2 groups by weight ,maize germ oil group and lard oil group. The mice were given maize germ oil or lard oil by gavage at a dose of 1 ml/100 mg BW, respectively, after over-night fasting. At 0, 30, 60, 120, 180 and 240 min after oil loading, 8 mice were selected randomly from both groups, respectively, and blood was collected via orbital bleeding for postprandial blood lipids and fatty acid profile analysis.
Results:
The serum triglycerides and total free fatty acids levels in mice loaded with lard oil were significantly higher than those in mice loaded with maize germ oil, respectively, at 120, 180, 240 min. The serum saturated fatty acids and monounsaturated fatty acids in mice loaded with lard oil were significantly higher, whereas serum polyunsaturated fatty acids were significantly lower than those in mice loaded with maize germ oil at 60, 120, 180 and 240 min (P < 0.05). Serum palmitic oil and oleic oil in mice loaded with lard oil were higher, whereas linoleic oil and arachidonic acid were lower than those in mice loaded with maize germ oil at 60, 120, 180 and 240 min (P < 0.05).
Conclusion:
Compared with maize germ oil, lard oil leads to higher postprandial serum triglycerides and saturated fatty acids levels, that may increase the risk of cardiovascular diseases.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP8016282	Lard oil		8016-28-2	Price

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