0

Copper-catalyzed Tandem Aerobic Oxidative Cyclization for the Synthesis of 4-cyanoalkylpyrrolo[1,2-a]quinoxalines From 1-(2-aminophenyl)pyrroles and Cyclobutanone Oxime Esters

Zhenyu An, Yong Jiang, Xin Guan, Rulong Yan

Chem Commun (Camb). 2018 Sep 20;54(76):10738-10741.

PMID: 30191218

Abstract:

A copper-catalyzed tandem ring-opening/cyclization reaction for the synthesis of 4-cyanoalkylpyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclobutanone oxime esters has been developed. This reaction involves C-C bond cleavage and C-C and C-N bond constructions with good functional group tolerance. A wide range of products are obtained in moderate to good yields under mild conditions.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AS24722 2-(Tetradecyl-d29)cyclobutanone 2-(Tetradecyl-d29)cyclobutanone Price
qrcode