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Copper-mediated N-cyclopropylation of Azoles, Amides, and Sulfonamides by Cyclopropylboronic Acid

Sébastien Bénard, Luc Neuville, Jieping Zhu

J Org Chem. 2008 Aug 15;73(16):6441-4.

PMID: 18610980

Abstract:

Reaction of azoles, amides, and sulfonamides in dichloroethane with readily available cyclopropylboronic acid in the presence of copper acetate and sodium carbonate afforded the N-cyclopropyl derivatives in good to excellent yields.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP411235579 Cyclopropylboronic acid Cyclopropylboronic acid 411235-57-9 Price
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