Home
Resources
Publications
Crystal Structures of heptakis(2,6-di-O-ethyl)cyclomaltoheptaose

Crystal Structures of heptakis(2,6-di-O-ethyl)cyclomaltoheptaose

K Harata, H Hirayama, K Uekama

Carbohydr Res. 2000 Nov 17;329(3):597-607.

PMID: 11128588

Abstract:

Heptakis(2,6-di-O-ethyl)-beta-cyclodextrin (DE-beta-CD) was crystallized in two forms from hexane and 95% aqueous methanol, respectively: A form I crystal with the space group P2(1)2(1)2(1) and a form II crystal with the space group P3(1). In both crystals, DE-beta-CD molecules are in a round shape with intramolecular O-3-H...O-2 hydrogen bonds. In the form I crystal, the DE-beta-CD molecules are arranged along the twofold screw axis to form a helically extended polymeric chain by including the 6-O-ethyl groups of the adjacent molecule. One hexane molecule with twofold disorder is located in the intermolecular channel along the a-axis. In contrast, the DE-beta-CD molecules in the form II crystal form a helical arrangement along the threefold screw axis. One methanol and one water molecule are included on the O-6 side of the molecular cavity. The water molecule links the methanol molecule and two ethoxy groups of the adjacent DE-beta-CD molecule with hydrogen bonds. The result suggests the important role of solvent in the formation of helical arrangement of DE-beta-CD molecules.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS741363	(2,6-Di-O-)ethyl-β-cyclodextrin			Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: