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Degradation of Cinnamic Acid by a Newly Isolated Bacterium

T R Monisha, Mukram Ismailsab, Ramesh Masarbo, Anand S Nayak, T B Karegoudar

3 Biotech. 2018 Aug;8(8):368.

PMID: 30105193

Abstract:

A bacterium Stenotrophomonas sp. TRMK2 capable of utilizing cinnamic acid was isolated from agro-industrial waste by enrichment culture technique. This strain completely utilizes 5 mM cinnamic acid within 18 h of incubation. The different metabolites formed during the degradation of cinnamic acid were characterized by GC-HRMS. The involvement of various enzymes, namely cinnamate reductase, 3-phenylpropionic acid hydroxylase, p-hydroxybenzoic acid hydroxylase and protocatechuate 3,4-dioxygenase in cinnamic acid degradation was demonstrated. A catabolic pathway for cinnamic acid in Stenotrophomonas sp. TRMK2 is as follows: Cinnamic acid; 3-Phenylpropionic acid; 3-(4-Hydroxyphenyl) propionic acid; 4-Hydroxy benzoic acid and Protocatechuic acid. Further, this strain is capable of utilizing various phenolic compounds.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP140103-B Cinnamic acid Cinnamic acid 140-10-3 Price
AP374538019 4-Fluoro-3-formylphenylboronic acid 4-Fluoro-3-formylphenylboronic acid 374538-01-9 Price
AP763120587 1H-Pyrazole-4-boronic acid 1H-Pyrazole-4-boronic acid 763120-58-7 Price
LS7931221 6-morpholinopyridin-3-ylboronic acid 6-morpholinopyridin-3-ylboronic acid Price
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