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Deposition of Aluminum in Brain Tissues of Rats Exposed to Inhalation of Aluminum Acetylacetonate

Deposition of Aluminum in Brain Tissues of Rats Exposed to Inhalation of Aluminum Acetylacetonate

P Zatta, M Favarato, M Nicolini

Neuroreport. 1993 Sep;4(9):1119-22.

PMID: 8219037

Abstract:

The present paper reports data concerning aluminum accumulation and compartmentation in the central nervous system from rats exposed by inhalation to aluminum acetylacetonate [Al(acac)3] for two weeks. The complex Al(aca)3 was chosen for being neutral, hydrolytically stable and lipophilic. After animals treatment, Al(III) was identified fluorimetrically by using morin (3,5,7',2',4'-pentahydroxyflavone) that gives a specific green-yellow fluorescence when complexed to the metal. Al(III) was observed to be accumulated in the brain cortex, hippocampus, enthorinal area, olfactory bulb as well as in the Purkinje cells of cerebellum, and in the white matter.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP13963570	Aluminum acetylacetonate		13963-57-0	Price

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