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Determination of Specific Absorbance (A¦) for Six Psychoactive Drugs Encountered in Forensic Toxicology

Determination of Specific Absorbance (A¦) for Six Psychoactive Drugs Encountered in Forensic Toxicology

Cat-Van Tran, Jay R Vargas

J Anal Toxicol. 2019 Nov 27;bkz091.

PMID: 31776558

Abstract:

Specific absorbance (A¦) is defined as the maximum absorbance of a 1% solution over a 1-cm path length as measured via spectroscopy. Finding a reliable value for specific absorbance for a drug provides an important tool for the quantitative verification of concentration of analytical standards. Although many new drugs have emerged within the last ten years, many of these drugs either do not have a reliable value for A¦, or a value simply has never been published. This work focused on determining the quantitative value of the specific absorbance of six psychoactive drugs using ultraviolet-visible spectroscopy, as well as comparing A¦ values of drugs purchased in 2017 to A¦ of their counterparts purchased in 2019. The drugs analyzed included Iloperidone, Risperidone, Aripiprazole, Vilazodone, Vortioxetine, and Suvorexant.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP133454474-A	Iloperidone solution		133454-47-4	Price

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