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Determination of UV-filters in Sunscreens by HPLC

Determination of UV-filters in Sunscreens by HPLC

A Chisvert, M C Pascual-Martí, A Salvador

Fresenius J Anal Chem. 2001 Apr;369(7-8):638-41.

PMID: 11371063

Abstract:

Simultaneous determination of six internationally authorised organic UV-filters in sunscreen formulations was performed by HPLC with UV spectrophotometric detection. The filters determined were: sulisobenzone, oxybenzone, octyl dimethyl PABA, octyl methoxycinnamate, octyl salicylate and homosalate. A C18 stationary phase and a mobile phase of ethanol water acetic acid (70:29.5:0.5) were used with a flow rate of 0.5 mL/min. UV measurements were carried out at 313 nm. The time required for the analysis was 25 min and the limits of detection were between 0.2 and 2 mg/L, except for sulisobenzone, which gave a limit of detection of 20 mg/L. The procedure proposed provides an accurate, fast and green analytical method, that does not involve toxic organic solvents.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP4065456-A	Sulisobenzone		4065-45-6	Price

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