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Developing Soluble Polymers for High-Throughput Synthetic Chemistry

Developing Soluble Polymers for High-Throughput Synthetic Chemistry

Carsten Spanka, Paul Wentworth Jr, Kim D Janda

Comb Chem High Throughput Screen. 2002 May;5(3):233-40.

PMID: 11966431

Abstract:

Soluble polymers have emerged as viable alternatives to resin supports across the broad spectrum of high-throughput organic chemistry. As the application of these supports become more widespread, issues such as broad-spectrum solubility and loading are becoming limiting factors and therefore new polymers are required to overcome such limitations. This article details the approach made within our group to new soluble polymer supports and specifically focuses on parallel libraries of block copolymers, de novo poly(styrene-co-chloromethylstyrene), PEG- stealth stars, and substituted poly(norbornylene)s.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
LS73336	Poly(styrene-co-chloromethylstyrene)			Price

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