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Dietary Nutraceuticals as Backbone for Bone Health

Dietary Nutraceuticals as Backbone for Bone Health

Manoj K Pandey, Subash C Gupta, Deepkamal Karelia, Patrick J Gilhooley, Mehdi Shakibaei, Bharat B Aggarwal

Biotechnol Adv. 2018 Nov 1;36(6):1633-1648.

PMID: 29597029

Abstract:

Bone loss or osteoporosis, is a slow-progressing disease that results from dysregulation of pro-inflammatory cytokines. The FDA has approved number of drugs for bone loss prevention, nonetheless all are expensive and have multiple side effects. The nutraceuticals identified from dietary agents such as butein, cardamonin, coronarin D curcumin, diosgenin, embelin, gambogic acid, genistein, plumbagin, quercetin, reseveratrol, zerumbone and more, can modulate cell signaling pathways and reverse/slow down osteoporosis. Most of these nutraceuticals are inexpensive; show no side effect while still possessing anti-inflammatory properties. This review provides various mechanisms of osteoporosis and how nutraceuticals can potentially prevent the bone loss.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP481425	Plumbagin		481-42-5	Price
AP550243-A	Embelin		550-24-3	Price

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