Dill

PMID: 30000937

Abstract:

Dill (Anethum graveolens) seeds contain essential oil rich in carvone and limonene, in addition to phenolics, such as trans-anethole, and flavonoids. Dill is a purported galactogogue.[1][2][3][4] No scientifically valid clinical trials support this use, and one small, old study found no galactogogue effect of a primary dill component, d-carvone.[5] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[6] Two studies found small, but measurable amounts of d-carvone in the milk of mothers given the chemical experimentally. Dill is "generally recognized as safe" (GRAS) as a food by the U.S. Food and Drug Administration. It is generally well tolerated, but occasional allergic skin reactions have been reported, especially after contact with fresh dill. In two studies, nursing mothers were given d-carvone. No adverse effects were noted in the mothers or infants. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information about dietary supplements is available elsewhere on the LactMed Web site.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP6485401	(−)-Carvone		6485-40-1	Price

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