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Dual Signaling of Hydrazine by Selective Deprotection of Dichlorofluorescein and Resorufin Acetates

Myung Gil Choi, Jung Ok Moon, Jihee Bae, Jung Woo Lee, Suk-Kyu Chang

Org Biomol Chem. 2013 May 14;11(18):2961-5.

PMID: 23487180

Abstract:

The highly selective chemosignaling behaviors for hydrazine by a reaction-based probe of dichlorofluorescein and resorufin acetates were investigated. Hydrazinolysis of latent dichlorofluorescein and resorufin acetate fluorochromes caused prominent chromogenic and fluorescent turn-on type signals. The probes selectively detected hydrazine in the presence of commonly encountered metal ions and anions as background. Dichlorofluorescein and resorufin acetates selectively detected hydrazine with detection limits of 9.0 × 10(-8) M and 8.2 × 10(-7) M, respectively. Furthermore, hydrazine was selectively detected over other closely related compounds, such as hydroxylamine, ethylenediamine, and ammonia. As a possible application of the acetate probes, hydrazine signaling in tap water was tested.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP1152143 Resorufin acetate Resorufin acetate 1152-14-3 Price
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