0

Eco-Friendly Syntheses of 2-Substituted Benzoxazoles and 2-Substituted Benzothiazoles From 2-Aminophenols, 2-Aminothiophenols and DMF Derivatives in the Presence of Imidazolium Chloride

Qingqiang Tian, Wen Luo, Zongjie Gan, Dan Li, Zeshu Dai, Huajun Wang, Xuetong Wang, Jianyong Yuan

Molecules. 2019 Jan 4;24(1):174.

PMID: 30621218

Abstract:

A simple, economical and metal-free approach to the synthesis of 2-substituted benzoxazoles and 2-substituted benzothiazoles from 2-aminophenols, 2-aminothiophenols and DMF derivatives, only using imidazolium chloride (50% mmol) as promoter without any other additive, was reported. Various 2-substituted benzoxazoles and 2-substituted benzothiazoles were thus prepared in moderate to excellent yields.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP136849031 PSS-Octa[2-(4-cyclohexenyl)ethyldimethylsilyloxy] substituted PSS-Octa[2-(4-cyclohexenyl)ethyldimethylsilyloxy] substituted 136849-03-1 Price
qrcode