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Effect of Calcium Dobesilate and Its Interaction With Aspirin on Thrombus Formation in Vivo

M Michal, N Giessinger

Thromb Res. 1985 Oct 15;40(2):215-26.

PMID: 4071471

Abstract:

The effect of calcium dobesilate (calcium dihydroxy-2,5 benzenesulphonate) on thrombus formation in vivo was evaluated. Experimental thrombi were induced in a venule of a hamster cheek pouch following iontophoresis of adenosine diphosphate (ADP). Calcium dobesilate administered intraperitoneally as a single injection inhibited thrombus formation in a time- and dose-dependent manner. Furthermore, the combination of calcium dobesilate and aspirin resulted in the potentiation of the inhibition of thrombus formation.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
ALP20123802 Dobesilate Calcium Dobesilate Calcium 20123-80-2 (anhydrous) Price
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