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Effect of (+)-catechin Hydrate on Oxidative Stress Induced by High Sucrose and High Fat Diet in Male Wistar Rats

Effect of (+)-catechin Hydrate on Oxidative Stress Induced by High Sucrose and High Fat Diet in Male Wistar Rats

Pranav Mehra, Meenakshi Garg, Ashwani Koul, Devi Dayal Bansal

Indian J Exp Biol. 2013 Oct;51(10):823-7.

PMID: 24266106

Abstract:

Increased lipid peroxidation and reduced glutathione levels in liver of rats fed high sucrose high fat (HSHF) diet were normalized by concomitant administration of (+)-catechin hydrate. Plasma non-enzymatic antioxidants viz. alpha-tocopherol, ascorbic acid and total thiols decrease were also significantly less in rats administered with (+)-catechin hydrate concomitantly with HSHF diet. Thus the present results indicate that (+)-catechin hydrate has antioxidant activity and is effective in reducing oxidative stress. The study is of clinical importance as oxidative stress is known to be the cause of many clinical manifestations viz. cancer, Parkinson's disease, atherosclerosis, heart failure, myocardial infarction and many other diseases.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
CS3102147	(±)-Catechin hydrate			Price

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