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Effect of Ocimum Gratissimum in Mouthrinses on De Novo Plaque Formation. A Randomized Clinical Trial

Effect of Ocimum Gratissimum in Mouthrinses on De Novo Plaque Formation. A Randomized Clinical Trial

Manoela Siqueira Pimenta, Nayana Santiago Guedis Lobo, Virna Castelo Vieira, Ângela Maria Alves da Costa, Flávio Nogueira da Costa, Sérgio Luís da Silva Pereira

Braz Dent J. Oct-Dec 2016;27(6):646-651.

PMID: 27982173

Abstract:

The aim of this study was to evaluate the antiplaque effect of Ocimum gratissimum (Og) by in vivo investigation. Fifteen healthy volunteers participated in a crossover, double-blind clinical study, using a 3-day partial-mouth plaque accumulation model. The participants abolished any method of mechanical oral hygiene and they were randomly assigned to initially use just the following mouthrinses: distilled water (DW solution), 0.12% chlorhexidine digluconate (CLX solution) or 10% Og (Og solution). The plaque index (PLI) was recorded in all mandibular teeth at the end of the trial and the Kruskal-Wallis (α=0.05) and Mann-Whitney (α=0.05) tests were used to estimate the difference among groups. The clinical results showed statistically significant difference among the groups (p<0.05), favoring the CLX solution and Og solution, but the first was more effective (p<0.05). The mouthrinses containing 0.12% chlorhexidine digluconate and 10% Og were able to inhibit plaque re-growth, however Og showed more limited results in comparison to CLX.

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