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Effect of Raw Winged Bean [Psophocarpus Tetragonolobus (L.) DC] Tuber Lectin on Gastrointestinal Tract of Growing Rats

Effect of Raw Winged Bean [Psophocarpus Tetragonolobus (L.) DC] Tuber Lectin on Gastrointestinal Tract of Growing Rats

M S Shet, M Madaiah, R N Ahamed

Indian J Exp Biol. 1989 Jan;27(1):58-61.

PMID: 2514144

Abstract:

The fraction containing high hemagglutinating activity was prepared from raw winged bean tubers and orally administered to growing rats. The food intake and body weights of these rats decreased as the level of lectin increased and significant lectin activity was detected in the faeces extracted from these rats which is anti-genically similar to the native lectin preparation. Microscopic examination has revealed morphological changes in the intestinal epithelial cells. The binding action of the lectin to the mucosal epithelia of the gastrointestinal tract is indicative of the deleterious effects caused by the winged bean tuber lectin.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR424656	Lectin from Psophocarpus tetragonolobus (winged bean)			Price

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