Home
Resources
Publications
Effect of the Phospholipid Chain Length and Head Group on Beta-Phase Formation of poly(9,9-dioctylfluorene) Enclosed in Liposomes

Effect of the Phospholipid Chain Length and Head Group on Beta-Phase Formation of poly(9,9-dioctylfluorene) Enclosed in Liposomes

María J Tapia, María Monteserín, Hugh D Burrows, João S Seixas de Melo, Joan Estelrich

Photochem Photobiol. Nov-Dec 2013;89(6):1471-8.

PMID: 23865822

Abstract:

We have studied the effect of head group and alkyl chain length on β-phase formation in poly(9,9-dioctylfluorene) (PFO) solubilized in phospholipid liposomes. Systems studied have three different alkyl chain lengths (1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine [DMPC], 1,2-didodecanoyl-sn-glycero-3-phosphatidylcholine [DLPC], 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine [DPPC]) and head groups (1,2-dimyristoyl-sn-glycero-3-phosphate monosodium salt [DMPA], 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine [DMPE] and 1,2-dimyristoyl-sn-glycero-3-phospho-l-serine sodium salt [DMPS]). Changes in liposome size upon addition of PFO are followed by dynamic light scattering. All the phospholipids induce the formation of PFO β-phase, which is followed by the emission intensity and deconvolution of the absorption spectra. Both the head group and alkyl chain length affect the yield of β-phase. The photophysics of PFO incorporated in liposomes is characterized by stationary and time-resolved fluorescence, whereas the polymer-phospholipid interactions have been studied by the effect of the PFO concentration on the phospholipid phase transitions (differential scanning calorimetry [DSC]).

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP105405503	1,2-Dimyristoyl-sn-glycero-3-phospho-L-serine sodium salt		105405-50-3	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: