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Effect of the Triterpenoid Miliacin on the Sensitivity of Lymphocytes in the Thymus and Spleen to Dexamethasone-Induced Apoptosis

T V Panfilova, A A Shtil', E R Polosukhina, A Yu Baryshnikov, B A Frolov

Bull Exp Biol Med. 2003 Oct;136(4):336-9.

PMID: 14714076

Abstract:

We studied the effect of plant triterpenoid miliacin on dexamethasone-induced apoptosis in thymocytes and splenocytes. Miliacin produced a protective effect on splenocytes by decreasing the degree of DNA fragmentation due to blockade of the cascade cell death distally to the intramembrane phosphatidylserine translocation.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP5945459 Miliacin Miliacin 5945-45-9 Price
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