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[Effect of Vitamin B12 Mixed Solution Inhalation for Acute Radiation-Induced Mucosal Injury]

[Effect of Vitamin B12 Mixed Solution Inhalation for Acute Radiation-Induced Mucosal Injury]

Xiang-long Chen, Yu-sheng Shi

Nan Fang Yi Ke Da Xue Xue Bao. 2006 Apr;26(4):512-4.

PMID: 16624769

Abstract:

Objective:
To evaluate the therapeutic effect of inhalation of vitamin B12 mixed solution in treating acute radiation-induced mucosal injury.
Methods:
Totally 122 patients with acute radiation-induced mucosal injury resulting from radiotherapy were divided into two equal groups and received vitamin B12 mixed solution inhalation and gentamycin sulfate mixed solution inhalation, respectively.
Results:
The patients receiving inhalation of vitamin B12 mixed solution showed favorable response to the treatment and the mucosal injury was alleviated as manifested by relieved pains, improved appetite and lessened body weight loss, which allowed uninterrupted administration of radiotherapy. In patients treated with inhalation of gentamycin sulfate mixed solution, by contrast, the mucosal injury was serious and in 8 patients radiotherapy had to be suspended for acute radiation-induced mucosal injury.
Conclusion:
Vitamin B12 mixed solution inhalation can be an effective treatment for acute radiation-induced mucosal injury.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
IAR42410575	Vitamin B12-(dimethylbenzimidazole-13C7) solution			Price

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