0

Efficient and Regioselective Ruthenium-Catalyzed Hydro-Aminomethylation of Olefins

Lipeng Wu, Ivana Fleischer, Ralf Jackstell, Matthias Beller

J Am Chem Soc. 2013 Mar 13;135(10):3989-96.

PMID: 23419202

Abstract:

An efficient and regioselective ruthenium-catalyzed hydroaminomethlyation of olefins is reported. Key to success is the use of specific 2-phosphino-substituted imidazole ligands and triruthenium dodecacarbonyl as catalyst. Both industrially important aliphatic as well as various functionalized olefins react with primary and secondary amines to give the corresponding secondary and tertiary amines generally in high yields (up to 96%) and excellent regioselectivities (n/iso up to 99:1).

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP15243331 Triruthenium dodecacarbonyl Triruthenium dodecacarbonyl 15243-33-1 Price
qrcode