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Efficient Esterification of Oxidized l-Glutathione and Other Small Peptides

Emily R Vogel, William Jackson, Douglas S Masterson

Molecules. 2015 Jun 8;20(6):10487-95.

PMID: 26060914

Abstract:

Oxidized l-glutathione was esterified to the tetra methyl ester using thionyl chloride in methanol solvent. Other alcohols were tested and the reaction progress was monitored via ESI-MS. This procedure proved to be compatible with other small peptides not containing serine and cysteine residues. In contrast to previously reported methods this procedure provided convenient access to esterified peptides requiring no purification, extended reaction times, or complicated reaction setups.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP27025418 L-Glutathione oxidized L-Glutathione oxidized 27025-41-8 Price
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