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Efficient Preparation of Optically Active Ketoprofen by Mucor Javanicus Lipase Immobilized on an Inorganic Support

K Kato, Y Gong, T Saito, H Kimoto

J Biosci Bioeng. 2000;90(3):332-4.

PMID: 16232865

Abstract:

Lipase M from Mucor javanicus, one of nine commercially available hydrolytic enzymes, showed good enantioselectivity (E=50) for racemic ketoprofen trifluoroethyl ester in phosphate buffer (pH 7.0) containing 30% acetone. Lipase M immobilized on Toyonite 200-A showed the best selectivity (E=55) and reactivity. Moreover, the lipase could be recycled at least 5 times.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP9001621-J Lipase from Mucor javanicus Lipase from Mucor javanicus 9001-62-1 Price
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