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Efficient Protiodesilylation of Unactivated C(sp3)-SiMe2Ph Bonds Using Tetrabutylammonium Fluoride

Cheryl L Heitzman, William T Lambert, Eric Mertz, J Brad Shotwell, Jennifer M Tinsley, Porino Va, William R Roush

Org Lett. 2005 Jun 9;7(12):2405-8.

PMID: 15932209

Abstract:

[reaction: see text] The protiodesilylation of unactivated C(sp3)-SiMe2Ph bonds proceeds efficiently by treatment with tetrabutylammonium fluoride in wet DMF or THF via isolable dimethylsilanol intermediates.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP879904822 (N-Boc-2-pyrrolyl)dimethylsilanol (N-Boc-2-pyrrolyl)dimethylsilanol 879904-82-2 Price
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