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Electrochemical, Manganese-Assisted Carbon-Carbon Bond Formation Between β-Keto Esters and Silyl Enol Ethers

Julia Strehl, Gerhard Hilt

Org Lett. 2019 Jul 5;21(13):5259-5263.

PMID: 31247778

Abstract:

The electrochemical carbon-carbon bond formation process between β-keto esters and silyl enol ethers was investigated utilizing manganese salts. The tricarbonyl compounds were generated in moderate to good yields under neutral conditions. Control experiments revealed that an electro-generated base at the cathode is important. Electroanalytical measurements with a Mn(TPA) complex suggested that the oxidation of the silyl enol ether is the first step in the oxidation process initiated by a corresponding Mn(IV) species.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP58204425 Triamminetungsten(IV) tricarbonyl Triamminetungsten(IV) tricarbonyl 58204-42-5 Price
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