Home
Resources
Publications
Electrospun Gelatin Fiber Mats Containing a herbal-Centella Asiatica-Extract and Release Characteristic of Asiaticoside

Electrospun Gelatin Fiber Mats Containing a herbal-Centella Asiatica-Extract and Release Characteristic of Asiaticoside

Panprung Sikareepaisan, Apichart Suksamrarn, Pitt Supaphol

Nanotechnology. 2008 Jan 9;19(1):015102.

PMID: 21730522

Abstract:

Ultra-fine gelatin (type A, porcine skin, ∼180 Bloom) fiber mats containing a methanolic crude extract of Centella asiatica (L.) Urban, a medicinal plant widely known for its traditional medical applications including its wound healing ability, were fabricated, for the first time, from the neat gelatin solution (22% w/v in 70 vol% acetic acid) containing the crude extract (mCA) in various amounts (i.e. 5-30 wt% based on the weight of gelatin powder) by electrospinning. Incorporation of mCA in the neat gelatin solution did not affect both the morphology and the size of the mCA-loaded gelatin fibers, as both of the neat and the mCA-loaded gelatin fibers were smooth and the average diameters of these fibers ranged between 226 and 232 nm. The cross-linked mCA-loaded e-spun gelatin fiber mat from the neat gelatin solution containing 30 wt% of mCA was further investigated for the release characteristic of asiaticoside, identified as the most active compound associated with the healing of wounds, in two different types of releasing medium, i.e. acetate buffer and the buffer containing 10 vol% of methanol, based on the thin-layer chromatography (TLC)-densitometry technique. Based on the unit weight of the actual amount of asiaticoside present in the specimens, the total amount of asiaticoside released from the fiber mat specimens was lower than that from the film counterparts while, based on the unit weight of the specimens, an opposite trend was observed.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP84696219	Powdered Centella Asiatica Extract		84696-21-9	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: