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Elucidation of the Biosynthesis of the di-C-glycosylflavone Isoschaftoside, an Allelopathic Component From Desmodium Spp. That Inhibits Striga Spp. Development

Mary L Hamilton, Serge P Kuate, Melissa Brazier-Hicks, John C Caulfield, Ruth Rose, Robert Edwards, Baldwyn Torto, John A Pickett, Antony M Hooper

Phytochemistry. 2012 Dec;84:169-76.

PMID: 22959223

Abstract:

Isoschaftoside, an allelopathic di-C-glycosylflavone from Desmodium spp. root exudates, is biosynthesised through sequential glucosylation and arabinosylation of 2-hydroxynaringenin with UDP-glucose and UDP-arabinose. Complete conversion to the flavone requires chemical dehydration implying a dehydratase enzyme has a role in vivo to complete the biosynthesis. The C-glucosyltransferase has been partially characterised and its activity demonstrated in highly purified fractions.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP52012290 Isoschaftoside Isoschaftoside 52012-29-0 Price
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