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Enantio- And Diastereoselective Reductive Aldol Reactions With Iridium-Pybox Catalysts

C X Zhao, M O Duffey, S J Taylor, J P Morken

Org Lett. 2001 Jun 14;3(12):1829-31.

PMID: 11405722

Abstract:

[see reaction]. A catalytic amount of [(cod)IrCl]2 and indane-pybox converts diethylmethylsilane, methyl acrylate, and certain aldehydes to the derived reductive aldol adduct with good enantio- and diastereocontrol.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP760327 Diethylmethylsilane Diethylmethylsilane 760-32-7 Price
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