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Enantioselective Oxidation of Racemic Lactic Acid to D-lactic Acid and Pyruvic Acid by Pseudomonas Stutzeri SDM

Chao Gao, Jianhua Qiu, Jingchen Li, Cuiqing Ma, Hongzhi Tang, Ping Xu

Bioresour Technol. 2009 Mar;100(5):1878-80.

PMID: 19000943

Abstract:

D-lactic acid and pyruvic acid are two important building block intermediates. Production of D-lactic acid and pyruvic acid from racemic lactic acid by biotransformation is economically interesting. Biocatalyst prepared from 9 g dry cell wt l(-1) of Pseudomonas stutzeri SDM could catalyze 45.00 g l(-1)DL-lactic acid into 25.23 g l(-1)D-lactic acid and 19.70 g l(-1) pyruvic acid in 10h. Using a simple ion exchange process, D-lactic acid and pyruvic acid were effectively separated from the biotransformation system. Co-production of d-lactic acid and pyruvic acid by enantioselective oxidation of racemic lactic acid is technically feasible.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP378785774 Pyruvic-13C3 acid Pyruvic-13C3 acid 378785-77-4 Price
AP7620282 D-2-Aminoadipic acid D-2-Aminoadipic acid 7620-28-2 Price
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