Esmolol

Aleksandr Pevtsov, Connor C. Kerndt, Katherine L. Fredlund

PMID: 30085507

Abstract:

Esmolol (esmolol hydrochloride) is an intravenous cardioselective beta-1 adrenergic antagonist. Esmolol is FDA-approved for short-term duration use in control of supraventricular tachycardia, such as a rapid ventricular rate in patients with atrial fibrillation or atrial flutter. Esmolol is used in various settings including urgent care, perioperatively, and postoperatively. It is also indicated in sinus tachycardia, where a rapid rate requires intervention secondary to other comorbidities. Esmolol is further FDA-approved for tachycardia and hypertension induced by intubation. Off-label, it is used for rate and rhythm control in aortic dissection, acute coronary syndrome, non-ST elevation myocardial infarction, hypertensive emergencies, thyrotoxicosis, refractory ventricular tachycardia, refractory to defibrillation ventricular fibrillation, and to decrease catecholamine response during electroconvulsive therapy.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP81161173	Esmolol hydrochloride		81161-17-3	Price

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