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Estimation of Boswellic Acids in Herbal Formulations Containing

Estimation of Boswellic Acids in Herbal Formulations Containing

Kumar Katragunta, Bandi Siva, Niharika Kondepudi, P R Rao Vadaparthi, Nadendla Rama Rao, Ashok Kumar Tiwari, Katragadda Suresh Babu

J Pharm Anal. 2019 Dec;9(6):414-422.

PMID: 31890341

Abstract:

Boswellia serrata is a widely used herb in Indian systems of medicine and is well known for its potential medicinal properties. A chromatographic method was developed for the analysis and quantification of six boswellic acid marker compounds, i.e., keto boswellic acid (1), 3-O-Acetyl 11-keto β-boswellic acid (2), ɑ-Boswellic acid (3), β-Boswellic acid (4), 3-O-Acetyl-ɑ-boswellic acid (5) and 3-O-Acetyl-β-boswellic acid (6) in commercial herbal products containing B. serrata as an ingredient. Combining UPLC with Q-Tof-MS/MS makes the better identification of secondary metabolites and adulterants in the herbal formulations containing B. serrata in rapid time using fragmentation approach than the traditional approaches. In this study quantification of boswellic acids with UPLC-PDA method was performed as per the pharmacopeia guidelines. Furthermore, minor phytochemical constituents were identified and characterized with the help of LC-Q-Tof-MS/MS fragmentation data and various isoforms of boswellic acids and tirucallic acids in B. serrata oleo-gum-resin extract were identified.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP5968707	3-O-Acetyl-β-boswellic acid		5968-70-7	Price

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