Home
Resources
Publications
Ethiodized Poppyseed Oil Versus Ioversol for Image Quality and Adverse Events in Hysterosalpingography: A Prospective Cohort Study

Ethiodized Poppyseed Oil Versus Ioversol for Image Quality and Adverse Events in Hysterosalpingography: A Prospective Cohort Study

Yiqing Tan, Shilin Zheng, Wenfeng Lei, Fuhua Wang, Shengpan Jiang, Ting Zeng, Bei Zhou, Fan Hong

BMC Med Imaging. 2019 Jun 24;19(1):50.

PMID: 31234782

Abstract:

Background:
This study aimed to investigate the image quality and adverse events (AEs) of ethiodized poppyseed oil (EPO) compared with ioversol as contrast agents in hysterosalpingography (HSG).
Methods:
Two hundred twenty-eight patients underwent HSG were consecutively recruited in this prospective cohort study, and were accordingly divided into EPO group (N = 165) and ioversol group (N = 63). The quality of image was assessed according to the European Guidelines on quality criteria for diagnostic radiographic images. AEs during, within 2 h and at 1-month post-HSG were recorded.
Results:
EPO displayed elevated image quality compared with ioversol including the total image quality score (P < 0.001), the cervical canal display score (P < 0.001), shape and outline of uterus score (P < 0.01), cervical mucosa or folds score (P < 0.001), oviduct isthmus score (P < 0.001), ampulla and fimbriae of oviduct score (P < 0.001) and celiac diffuse image score (P < 0.001). Multivariate linear regression displayed that EPO (P < 0.001) was an independent predictive factor for increased total image quality score. AEs were similar between EPO group and ioversol group during and within 2 h post-HSG (all P > 0.05). However, at 1-month post-HSG, the number of patients had unchanged and faded menstrual blood color decreased but the proportion of patients with deepened menstrual color increased in EPO group compared with ioversol group (P = 0.007). In addition, the number of patients had iodine residue in uterine cavity was elevated in EPO group compared with ioversol group (P < 0.001).
Conclusion:
EPO is more efficient in image quality and equally tolerant compared to ioversol as contrast agents in HSG.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP87771402	Ioversol		87771-40-2	Price

As a specialist in analytical chemical Products, Alfa Chemistry offers consumers a wealth of raw materials and a full range of technologies and services.

QUICK LINKS

HEADQUARTERS

Tel:

Fax:

Email: