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Evaluation of Chitosan Quaternary Ammonium Salt-Modified Resin Denture Base Material

Rong Song, Zhaohua Zhong, Lexun Lin

Int J Biol Macromol. 2016 Apr;85:102-10.

PMID: 26718869

Abstract:

Chitosan quaternary ammonium salt displays good antioxidant and antibacterial characteristics and it shows appreciable solubility in water. When added to the traditional denture material to form a resin base, it could promote good oral health by improving the oral environment. In this study, chitosan quaternary ammonium salt was added to the denture material following two different methods. After three months of immersion in artificial saliva, the specimens were tested for tensile strength and were scanned by electron microscope. The murine fibroblast cytotoxicity and antibacterial properties were also tested. The result showed no significant differences in the tensile strength and in the proliferation of murine L929 fibroblast cells. The two structures of chitosan quaternary ammonium salt-modified denture material had different degrees of corrosion resistance and antimicrobial properties. These results indicate that chitosan quaternary ammonium salt-modified resin denture base material has the potential to become a new generation oral denture composite material.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP139893439 Tenivastatin ammonium salt Tenivastatin ammonium salt 139893-43-9 Price
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