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Evaluation of the Effect of Drugs on the Cyst Form of Toxoplasma Gondii

J Huskinson-Mark, F G Araujo, J S Remington

J Infect Dis. 1991 Jul;164(1):170-1.

PMID: 1647421

Abstract:

The cyst form of Toxoplasma gondii has been implicated as a cause of recrudescence of the latent infection in congenitally infected patients and in the immunocompromised host. A method was developed to evaluate the effect of drugs on the cyst form of the parasite and used to evaluate a variety of therapeutic agents. The most active compounds against the cyst form in vitro were arprinocid-N-oxide, azithromycin, and the hydroxynaphthoquinone 566C80.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP90503063 Azithromycin N-oxide Azithromycin N-oxide 90503-06-3 Price
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