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Evaluation of Xylazine Hydrochloride as the Sole Immobilizing Agent in Moose and Caribou--And Its Subsequent Reversal With Idazoxan

Evaluation of Xylazine Hydrochloride as the Sole Immobilizing Agent in Moose and Caribou--And Its Subsequent Reversal With Idazoxan

T J Doherty, D P Tweedie

J Wildl Dis. 1989 Jan;25(1):95-8.

PMID: 2563404

Abstract:

Xylazine hydrochloride was used as the sole immobilizing agent in moose and caribou. The animals were free-ranging and immobilization was accomplished from a helicopter using powered darts. Following a period of immobilization during which radiotelemetry collars were fitted, the animals were revived using idazoxan (RX 781094) or its methoxy analogue RX 821002. Xylazine was administered at dose rates of approximately 3.0 mg/kg and 5.0 mg/kg to the moose and caribou, respectively. Moose received 430 +/- 27 mg of xylazine and a mean dose of 10 mg idazoxan (RX 781094). Caribou received 485 +/- 30 mg xylazine and a mean dose of 4 mg idazoxan (RX 821002). This technique gave adequate immobilization with rapid recovery of consciousness in both species.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP109544458	RX 821002 hydrochloride		109544-45-8	Price

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