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Familial Hypercholesterolemia

Victoria Enchia Bouhairie, Anne Carol Goldberg

Cardiol Clin. 2015 May;33(2):169-79.

PMID: 25939291

Abstract:

Familial hypercholesterolemia is a common, inherited disorder of cholesterol metabolism that leads to early cardiovascular morbidity and mortality. It is underdiagnosed and undertreated. Statins, ezetimibe, bile acid sequestrants, niacin, lomitapide, mipomersen, and low-density lipoprotein (LDL) apheresis are treatments that can lower LDL cholesterol levels. Early treatment can lead to substantial reduction of cardiovascular events and death in patients with familial hypercholesterolemia. It is important to increase awareness of this disorder in physicians and patients to reduce the burden of this disorder.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP182431125 Lomitapide Lomitapide 182431-12-5 Price
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