0

Fe(ii)-Catalyzed Alkenylation of Benzylic C-H Bonds With Diazo Compounds

Jiang-Ling Shi, Qinyu Luo, Weizhi Yu, Bo Wang, Zhang-Jie Shi, Jianbo Wang

Chem Commun (Camb). 2019 Apr 2;55(28):4047-4050.

PMID: 30869685

Abstract:

We report herein an alkenylation of benzylic C(sp3)-H bonds with diazo compounds via carbon cation intermediates with DDQ as the oxidant in the presence of a catalytic amount of Fe(ii). Diphenylmethane, toluene, benzyl methyl sulfide and their derivatives could be applied as substrates to afford the tetra-substituted olefin products, which may serve as useful building blocks in organic synthesis.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP766927 Benzyl methyl sulfide Benzyl methyl sulfide 766-92-7 Price
qrcode