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Feeding Responses to Mu-, Delta- And Kappa-Opioid Receptor Agonists in the Meat-Type Chick

Feeding Responses to Mu-, Delta- And Kappa-Opioid Receptor Agonists in the Meat-Type Chick

Takashi Bungo, Kazuya Kawamura, Tomofumi Izumi, Koh-Ichi Dodo, Hiroshi Ueda

Pharmacol Biochem Behav. 2004 Aug;78(4):707-10.

PMID: 15301925

Abstract:

The present study was designed to examine the effect of specific opioid agonists on feeding behavior in neonatal chicks. The food intake of broiler chicks was significantly decreased by intracerebroventricular injection of DAMGO and beta-casomorphin, micro-opioid receptor agonists, at 30-min postinjection. In contrast, both delta-opioid receptor agonists (DADLE and DPDPE) stimulated the food intake of the chick. Similar to the delta-opioid receptor agonists, food intake was elevated by the kappa-opioid receptor agonist (U-50488H and U-62066) in a dose-dependent manner. These results suggest that the endogenous opioid peptides have an important role for feeding behavior in the central nervous system of chicks.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP87151857	U-62066		87151-85-7	Price

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