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Fibroblast Growth Factor (FGF)-9 Immunoreactivity in Senile Plaques

S Nakamura, K Arima, S Haga, T Aizawa, Y Motoi, M Otsuka, A Ueki, K Ikeda

Brain Res. 1998 Dec 14;814(1-2):222-5.

PMID: 9838127

Abstract:

We examined fibroblast growth factor (FGF)-9 immunoreactivity in human hippocampal sections of Alzheimer's disease (AD). FGF-9 immunoreactivity was observed in dystrophic neurites of senile plaques in AD and control cases, in addition to the hippocampal and cortical neurons. The amyloid core and neurofibrillary tangles lacked immunoreactivity. FGF-9 immunoreactive astrocytes were conspicuous in AD brains. FGF-9 may be involved in the neuropathology of AD.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
IAR42413254 FGF-9 human FGF-9 human Price
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