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Formal Total Synthesis of Selaginpulvilin D

Bhavani Shankar Chinta, Beeraiah Baire

Org Biomol Chem. 2017 Jul 19;15(28):5908-5911.

PMID: 28534921

Abstract:

An efficient and mild synthetic strategy for the total synthesis of selaginpulvilin D has been reported. A highly chemoselective enyne-alkyne dehydro Diels-Alder reaction has been employed for the construction of the tricyclic fluorene framework present in the natural product selaginpulvilin D. An improved overall yield (10.5%) has been achieved for selaginpulvilin D, starting from commercially available m-anisaldehyde in 9 linear, operationally simple synthetic transformations.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP591311 m-Anisaldehyde m-Anisaldehyde 591-31-1 Price
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