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Frequency of Urinary Tract Infection and Antibiotic Sensitivity of Uropathogens in Patients With Diabetes

Frequency of Urinary Tract Infection and Antibiotic Sensitivity of Uropathogens in Patients With Diabetes

Kaleem Ullah Zubair, Abdul Haleem Shah, Asher Fawwad, Rubina Sabir, Anum Butt

Pak J Med Sci. Nov-Dec 2019;35(6):1664-1668.

PMID: 31777512

Abstract:

Objective:
To determine the frequency of urinary tract infections and antibiotic sensitivity among patients with diabetes.
Methods:
This observational study was carried out in Microbiology Department of Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University from April 2015 to June 2016. All patients with diabetes having symptoms of UTI attending out patients department of BIDE were analyzed. All samples received in the laboratory were processed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Antimicrobial susceptibility pattern was determined by disc diffusion method.
Results:
A total number of 199 urine specimens, frequency of UTI were 24 (12.06%) in male and 175 (87.94%) in female. UTIs were highly found in (age group 51-60) 70 (35.18%). Escherichia coli was the most frequent pathogen (71%), followed by Klebsiellapneumoniae (7.48%), Proteus mirabilis (1.87%), Staphylococcus aureus (9.35%), Candida (5.61%) and Candidaalbicans were (2.80%). Majority of gram negative uropathogens were shown high sensitivity towards Imipenem and Piperacillin / Tazobactam followed by Nitrofurantion, Ceftriaxone, Levofloxacin, Ofloxacine, Ciprofloxacin, Norfloxacin, Cefixime, Nalidixic acid and Cephradine. Gram positive was most sensitive to Nitrofurantionand Vancomycin followed by Piperacillin / Tazobactam, Imipenem, Cephradine, Ceftriaxone, Norfloxacin and Cefixime.
Conclusion:
We observed the higher frequency of UTIs in female as compared to male participants due to poor hygiene. E.coli was the most frequent pathogen responsible for UTI in patients with diabetes, followed by Staphylococcus aureus.

Chemicals Related in the Paper:

Catalog Number	Product Name	Structure	CAS Number	Price
AP58456863	Cephradine		58456-86-3	Price

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